瑜珈與按摩治療乳癌倖存者與芳香酶抑製劑相關的膝關節疼痛:一項隨機對照試驗

Sci Rep. 2021; 11: 14843.

Aromatase inhibitors (AIs) are standard adjuvant therapy for postmenopausal women with oestrogen receptor-positive, early-stage, and metastatic breast cancer. Although effective, the risk of falls due to AI-associated knee joint pain significantly increased. The aim of this study was to evaluate the therapeutic effects of yoga and massage on AI-associated knee joint pain. Breast cancer survivors were randomly assigned to a 6-week yoga intervention-2-week rest-6-week massage exposure (Yoga first, n = 30) or a 6-week massage intervention-2-week rest-6-week yoga exposure (Massage first, n = 30). Evaluations of the treatment efficacy were made at baseline, post-intervention, and post-exposure using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale, plasma cytokine levels, and changes in meridian energy. The results showed that yoga, superior to massage intervention, significantly reduced AI-associated knee joint pain, as demonstrated by the WOMAC pain score. The yoga intervention improvements were also associated with changes in plasma cytokine levels and meridian energy changes. In conclusion, this study provides scientific evidence that yoga was more effective than massage for reducing AI-associated knee joint pain. Meridian energy changes may provide another scientific, objective, non-invasive way to monitor the therapeutic effects of yoga and investigate another alternative, complementary medicine.

 

瑜珈與按摩治療乳癌倖存者與芳香酶抑製劑相關的膝關節疼痛:一項隨機對照試驗

Sci Rep. 2021; 11: 14843.

芳香化酶抑製劑是停經後雌激素受體陽性、早期和轉移性乳癌倖存者的標準輔助治療。儘管有效,但因該治療造成膝關節疼痛而跌倒的風險顯著增加。本研究目的評估瑜珈按摩對芳香化酶抑製劑造成膝關節疼痛的改善效果。乳癌倖存者被隨機分配到 6 周瑜伽干預 - 2 週休息 - 6 週按摩暴露(瑜珈第一,n = 30)或 6 週按摩干預 - 2 週休息 - 6 周瑜珈暴露(按摩第一,n = 30)。紀錄基線、干預後和暴露後西安大略與麥克馬斯特大學骨關節炎指數量表、血漿細胞激素因子水平和經絡能量變化以評估治療效果。我們的研究結果顯示,瑜珈優於按摩干預,能顯著減輕芳香化酶抑製劑治療造成的膝關節疼痛。研究並指出瑜珈干預的改善與降低血漿細胞激素因子水平及經絡能量變化有關。本研究提供科學證據說明瑜珈比按摩能更有效地減輕芳香化酶抑製劑治療造成的膝關節疼痛。經絡能量變化提供另一種科學、客觀、非侵入性的方式來監測瑜伽治療效果研究替代補充醫學。

https://www.nature.com/articles/s41598-021-94466-0